Gynecologic Cancer InterGroup (GCIG) consensus review for carcinoid tumors of the ovary.
Identifieur interne : 003882 ( Main/Exploration ); précédent : 003881; suivant : 003883Gynecologic Cancer InterGroup (GCIG) consensus review for carcinoid tumors of the ovary.
Auteurs : Nicholas Simon Reed ; Eva Gomez-Garcia ; Dolores Gallardo-Rincon ; Brigitte Barrette ; Klaus Baumann ; Michael Friedlander ; Ganessan Kichenadasse ; Jae-Weon Kim ; Domenica Lorusso ; Mansoor Raza Mirza ; Isabelle Ray-CoquardSource :
- International journal of gynecological cancer : official journal of the International Gynecological Cancer Society [ 1525-1438 ] ; 2014.
Descripteurs français
- KwdFr :
- MESH :
English descriptors
- KwdEn :
- MESH :
- pathology : Carcinoid Tumor, Ovarian Neoplasms.
- therapy : Carcinoid Tumor, Ovarian Neoplasms.
- Combined Modality Therapy, Consensus, Female, Humans, Medical Oncology, Practice Guidelines as Topic, Societies, Medical.
Abstract
Neuroendocrine tumors (NETs) are a heterogeneous group of neoplasms most commonly occurring in the gastrointestinal tract or the lungs. More frequent are gastrointestinal tumors, but over the past 30 years, there have been a number of small series or anecdotal case reports on ovarian NETs. Neuroendocrine tumors in the gynecologic tract are uncommon and account for about 2% of all gynecologic malignancies but may also be metastatic from other sites. They require a multimodality therapeutic approach determined by the extent of disease and the primary organ of involvement. Pathological diagnosis is critical to guide therapy. Surgery is the cornerstone of treatment for localized disease. There have been many new developments for treatment of advanced NETs including somatostatin analogs, hepatic artery embolization, chemotherapy, interferons, mammalian target of rapamycin inhibitors and radiolabeled somatostatin analogs. Given the rarity and lack of level I evidence, this is by nature more of a guidance and recommendation for management of these rare tumors until we can mount international studies.
DOI: 10.1097/IGC.0000000000000265
PubMed: 25341578
Affiliations:
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<term>Female</term>
<term>Humans</term>
<term>Medical Oncology</term>
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<term>Oncologie médicale</term>
<term>Sociétés médicales</term>
<term>Tumeur carcinoïde ()</term>
<term>Tumeur carcinoïde (anatomopathologie)</term>
<term>Tumeurs de l'ovaire ()</term>
<term>Tumeurs de l'ovaire (anatomopathologie)</term>
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<front><div type="abstract" xml:lang="en">Neuroendocrine tumors (NETs) are a heterogeneous group of neoplasms most commonly occurring in the gastrointestinal tract or the lungs. More frequent are gastrointestinal tumors, but over the past 30 years, there have been a number of small series or anecdotal case reports on ovarian NETs. Neuroendocrine tumors in the gynecologic tract are uncommon and account for about 2% of all gynecologic malignancies but may also be metastatic from other sites. They require a multimodality therapeutic approach determined by the extent of disease and the primary organ of involvement. Pathological diagnosis is critical to guide therapy. Surgery is the cornerstone of treatment for localized disease. There have been many new developments for treatment of advanced NETs including somatostatin analogs, hepatic artery embolization, chemotherapy, interferons, mammalian target of rapamycin inhibitors and radiolabeled somatostatin analogs. Given the rarity and lack of level I evidence, this is by nature more of a guidance and recommendation for management of these rare tumors until we can mount international studies.</div>
</front>
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<affiliations><list></list>
<tree><noCountry><name sortKey="Barrette, Brigitte" sort="Barrette, Brigitte" uniqKey="Barrette B" first="Brigitte" last="Barrette">Brigitte Barrette</name>
<name sortKey="Baumann, Klaus" sort="Baumann, Klaus" uniqKey="Baumann K" first="Klaus" last="Baumann">Klaus Baumann</name>
<name sortKey="Friedlander, Michael" sort="Friedlander, Michael" uniqKey="Friedlander M" first="Michael" last="Friedlander">Michael Friedlander</name>
<name sortKey="Gallardo Rincon, Dolores" sort="Gallardo Rincon, Dolores" uniqKey="Gallardo Rincon D" first="Dolores" last="Gallardo-Rincon">Dolores Gallardo-Rincon</name>
<name sortKey="Gomez Garcia, Eva" sort="Gomez Garcia, Eva" uniqKey="Gomez Garcia E" first="Eva" last="Gomez-Garcia">Eva Gomez-Garcia</name>
<name sortKey="Kichenadasse, Ganessan" sort="Kichenadasse, Ganessan" uniqKey="Kichenadasse G" first="Ganessan" last="Kichenadasse">Ganessan Kichenadasse</name>
<name sortKey="Kim, Jae Weon" sort="Kim, Jae Weon" uniqKey="Kim J" first="Jae-Weon" last="Kim">Jae-Weon Kim</name>
<name sortKey="Lorusso, Domenica" sort="Lorusso, Domenica" uniqKey="Lorusso D" first="Domenica" last="Lorusso">Domenica Lorusso</name>
<name sortKey="Mirza, Mansoor Raza" sort="Mirza, Mansoor Raza" uniqKey="Mirza M" first="Mansoor Raza" last="Mirza">Mansoor Raza Mirza</name>
<name sortKey="Ray Coquard, Isabelle" sort="Ray Coquard, Isabelle" uniqKey="Ray Coquard I" first="Isabelle" last="Ray-Coquard">Isabelle Ray-Coquard</name>
<name sortKey="Reed, Nicholas Simon" sort="Reed, Nicholas Simon" uniqKey="Reed N" first="Nicholas Simon" last="Reed">Nicholas Simon Reed</name>
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